San Francisco 49ers @ Arizona Cardinals
Sun Jan 10, 4:05 PM ET
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Odds from the latest scan: September 7, 12:19 AM ET. Live odds for this game.
DraftKings pays the most on San Francisco 49ers at -425, and DraftKings pays the most on Arizona Cardinals at +330.
Best NFL price on San Francisco 49ers vs Arizona Cardinals, compared across every major US sportsbook plus Kalshi, Polymarket US, ProphetX and Novig. Sun Jan 10, 4:05 PM ET.
Games starting within 24 hours refresh every minute; later games every 30 minutes and every hour as kickoff approaches during the beta; the free board refreshes hourly.
Moneyline Line HistorySan Francisco 49ers -425 DraftKings·Arizona Cardinals +330 DraftKings
Spread Line HistorySan Francisco 49ers -8.5 (-110) DraftKings·Arizona Cardinals +8.5 (-110) DraftKings
Total Line HistoryOver 44.5 (-110) DraftKings·Under 44.5 (-110) DraftKings
About These Charts
Player Props
1 books priced this game. Prediction market prices include trading fees wherever a fee applies, so they are directly comparable to sportsbook lines.
On San Francisco 49ers vs Arizona Cardinals, the best available price is not the same at every book. One sportsbook might post a side at -110 while another has it at -102, and taking the better number is the one edge you fully control. The Odds Gap scans every major US sportsbook plus the federally regulated prediction markets and flags where the best price sits on each side of this NFL matchup.
How to read these San Francisco 49ers vs Arizona Cardinals odds
The cards above show the best moneyline price on each side and which book has it. The spread line shows Arizona Cardinals at the market's consensus number, priced at the best odds among books quoting it. The total shows the Over at the consensus number. For every book's price on every market, open the game in the Line Shop.
San Francisco 49ers vs Arizona Cardinals Odds: Common Questions
Who has the best odds on San Francisco 49ers vs Arizona Cardinals?
At the latest scan DraftKings pays the most on San Francisco 49ers at -425, and DraftKings pays the most on Arizona Cardinals at +330. Those are two different books more often than not, and the best number moves as books reprice, so check the table on this page before you bet rather than assuming one book wins both sides.
What is the spread and total for San Francisco 49ers vs Arizona Cardinals?
The consensus spread is +8.5 on Arizona Cardinals with the best juice at -110 (DraftKings), and the consensus total is 44.5 with the best Over price at -110 (DraftKings). Consensus means the line most books agree on; the flagged price is the best juice available at that same number.
How often do these NFL odds update?
The free board rescans every hour from 7am to 1am ET; Live Beta, free with an email signup during the beta, refreshes every minute. This page was last scanned September 7, 12:19 AM ET, and that timestamp is shown above the table.
Does The Odds Gap pick a side on San Francisco 49ers vs Arizona Cardinals?
No. There is no model, no projection, and no lean anywhere on this site. We show which book pays the most on a bet you have already decided to make. Math, not picks.
Next Up For These Teams
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