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HomeNFL Odds › Miami Dolphins vs San Francisco 49ers

Miami Dolphins @ San Francisco 49ers

Sun Sep 20, 4:25 PM ET

Odds from the latest scan: August 19, 9:05 PM ET.

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DraftKings pays the most on Miami Dolphins at +455, and Caesars pays the most on San Francisco 49ers at -550. Across the 2 books pricing this game the best and worst numbers are $55.00 apart on a $100 bet.

Best NFL price on Miami Dolphins vs San Francisco 49ers, compared across every major US sportsbook plus Kalshi, Polymarket US, ProphetX and Novig. Sun Sep 20, 4:25 PM ET.

Games starting within 24 hours refresh every minute; later games every 30 minutes and every hour as kickoff approaches during the beta; the free board refreshes hourly.

Moneyline Line HistoryMiami Dolphins +455 DraftKings·San Francisco 49ers -550 Caesars
Miami Dolphins (away)
+455
Best at DraftKings
San Francisco 49ers (home)
-550
Best at Caesars

Every Book's Moneyline

BookMiami DolphinsSan Francisco 49ers
Caesars +400 -550
DraftKings +455 -625
Spread Line HistoryMiami Dolphins +10.5 (-110) DraftKings·San Francisco 49ers -10.5 (-110) DraftKings
Miami Dolphins
+10.5
-110
Best at DraftKings
San Francisco 49ers
-10.5
-110
Best at DraftKings
Total Line HistoryOver 46.5 (-110) DraftKings·Under 46.5 (-110) DraftKings
Over
O 46.5
-110
Best at DraftKings
Under
U 46.5
-110
Best at DraftKings
See every book's price in the Line Shop →

2 books priced this game. Prediction market prices include trading fees wherever a fee applies, so they are directly comparable to sportsbook lines.

On Miami Dolphins vs San Francisco 49ers, the best available price is not the same at every book. One sportsbook might post a side at -110 while another has it at -102, and taking the better number is the one edge you fully control. The Odds Gap scans every major US sportsbook plus the federally regulated prediction markets and flags where the best price sits on each side of this NFL matchup.

How to read these Miami Dolphins vs San Francisco 49ers odds

The cards above show the best moneyline price on each side and which book has it. The spread line shows San Francisco 49ers at the market's consensus number, priced at the best odds among books quoting it. The total shows the Over at the consensus number. For every book's price on every market, open the game in the Line Shop.

What the Price Gap Is Worth

Across the 2 books quoting this side, the best price is +455 at DraftKings and the worst is +400 at Caesars. Same bet, same outcome, $55.00 difference in profit on a $100 stake. Nothing about the wager changes, only where you place it.

Miami Dolphins vs San Francisco 49ers Odds: Common Questions

Who has the best odds on Miami Dolphins vs San Francisco 49ers?

At the latest scan DraftKings pays the most on Miami Dolphins at +455, and Caesars pays the most on San Francisco 49ers at -550. Those are two different books more often than not, and the best number moves as books reprice, so check the table on this page before you bet rather than assuming one book wins both sides.

How much does the price differ between sportsbooks on this game?

Right now 2 books price this side, and the spread between the best and worst of them is +455 at DraftKings versus +400 at Caesars. On a $100 bet that is $55.00 more in your pocket for the same wager, won or lost the same way. That difference is the entire reason this page exists.

What is the spread and total for Miami Dolphins vs San Francisco 49ers?

The consensus spread is -10.5 on San Francisco 49ers with the best juice at -110 (DraftKings), and the consensus total is 46.5 with the best Over price at -110 (DraftKings). Consensus means the line most books agree on; the flagged price is the best juice available at that same number.

How often do these NFL odds update?

The free board rescans every hour from 7am to 9pm ET; Live Beta, free with an email signup during the beta, refreshes every minute. This page was last scanned August 19, 9:05 PM ET, and that timestamp is shown above the table.

Does The Odds Gap pick a side on Miami Dolphins vs San Francisco 49ers?

No. There is no model, no projection, and no lean anywhere on this site. We show which book pays the most on a bet you have already decided to make. Math, not picks.

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