Detroit Lions @ Buffalo Bills
Thu Sep 17, 8:15 PM ET
Odds from the latest scan: August 19, 10:34 PM ET.
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theScore Bet pays the most on Detroit Lions at +140, and Caesars pays the most on Buffalo Bills at -159. Across the 6 books pricing this game the best and worst numbers are $7.00 apart on a $100 bet.
Best NFL price on Detroit Lions vs Buffalo Bills, compared across every major US sportsbook plus Kalshi, Polymarket US, ProphetX and Novig. Thu Sep 17, 8:15 PM ET.
Games starting within 24 hours refresh every minute; later games every 30 minutes and every hour as kickoff approaches during the beta; the free board refreshes hourly.
Moneyline Line HistoryDetroit Lions +140 theScore Bet·Buffalo Bills -159 Caesars
Every Book's Moneyline
| Book | Detroit Lions | Buffalo Bills |
|---|---|---|
| Caesars | +135 | -159 |
| DraftKings | +136 | -162 |
| theScore Bet | +140 | -165 |
| Bally Bet | +135 | -165 |
| BetParx | +135 | -165 |
| BetRivers | +133 | -165 |
Spread Line HistoryDetroit Lions +3 (+105) LowVig·Buffalo Bills -3 (-105) Bally Bet
Total Line HistoryOver 52.5 (-108) Caesars·Under 52.5 (-110) DraftKings
About These Charts
Player Props
6 books priced this game. Prediction market prices include trading fees wherever a fee applies, so they are directly comparable to sportsbook lines.
On Detroit Lions vs Buffalo Bills, the best available price is not the same at every book. One sportsbook might post a side at -110 while another has it at -102, and taking the better number is the one edge you fully control. The Odds Gap scans every major US sportsbook plus the federally regulated prediction markets and flags where the best price sits on each side of this NFL matchup.
How to read these Detroit Lions vs Buffalo Bills odds
The cards above show the best moneyline price on each side and which book has it. The spread line shows Buffalo Bills at the market's consensus number, priced at the best odds among books quoting it. The total shows the Over at the consensus number. For every book's price on every market, open the game in the Line Shop.
What the Price Gap Is Worth
Across the 6 books quoting this side, the best price is +140 at theScore Bet and the worst is +133 at BetRivers. Same bet, same outcome, $7.00 difference in profit on a $100 stake. Nothing about the wager changes, only where you place it.
- Detroit Lions: best +140 (theScore Bet), worst +133 (BetRivers)
- Buffalo Bills: best -159 (Caesars), worst -165 (theScore Bet)
Detroit Lions vs Buffalo Bills Odds: Common Questions
Who has the best odds on Detroit Lions vs Buffalo Bills?
At the latest scan theScore Bet pays the most on Detroit Lions at +140, and Caesars pays the most on Buffalo Bills at -159. Those are two different books more often than not, and the best number moves as books reprice, so check the table on this page before you bet rather than assuming one book wins both sides.
How much does the price differ between sportsbooks on this game?
Right now 6 books price this side, and the spread between the best and worst of them is +140 at theScore Bet versus +133 at BetRivers. On a $100 bet that is $7.00 more in your pocket for the same wager, won or lost the same way. That difference is the entire reason this page exists.
What is the spread and total for Detroit Lions vs Buffalo Bills?
The consensus spread is -3 on Buffalo Bills with the best juice at -105 (Bally Bet), and the consensus total is 52.5 with the best Over price at -108 (Caesars). Consensus means the line most books agree on; the flagged price is the best juice available at that same number.
How often do these NFL odds update?
The free board rescans every hour from 7am to 9pm ET; Live Beta, free with an email signup during the beta, refreshes every minute. This page was last scanned August 19, 10:34 PM ET, and that timestamp is shown above the table.
Does The Odds Gap pick a side on Detroit Lions vs Buffalo Bills?
No. There is no model, no projection, and no lean anywhere on this site. We show which book pays the most on a bet you have already decided to make. Math, not picks.
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